Kidney classified in four different part and function. kidney diseases affect different parts of kidney. Some example are, kidney tumor usually occurs in renal cortex, renal column hypertrophy may exist in renal column, medulla cystic kidney disease usually exists in renal medulla, and transitional cell cancer, renal pelvis and ureter cancer may attack renal pelvis. To propose automatically segment kidney in to four parts, to detect disease occurs in kidney scan image.Random forestmethod and modified 3DActive Appearance Model can performed.