An experimental study was conducted to investigate the durability properties of High Performance Concrete (HPC) by using copper slag and fly ash as a partial replacement of cement and fine aggregate and results have been discussed in this paper. M40 grade were used with different proportions of copper slag by 0% control, 15%, 30%, 45%, 60% and 75% with 20% of fly ash by the volume of cement. Chemical admixture such as conplast SP430 is used at the rate of 1.2% of cement which improves the workability of concrete. The main objective of this study is to determine the durability properties such as acid attack and alkaline attack in the concrete. Test results shows that the durability properties of concrete has improved by using copper slag as a partial replacement of sand upto 45% with 20% fly ash. Hence, high performance concrete found to be lower to acid and alkaline attack when compared to conventional concrete.